An obesogenic feedforward loop involving PPARγ, acyl-CoA binding protein and GABA(A) receptor

Acyl-coenzyme-A-binding protein (ACBP), also known as a diazepam-binding inhibitor (DBI), is a potent stimulator of appetite and lipogenesis. Bioinformatic analyses combined with systematic screens revealed that peroxisome proliferator-activated receptor gamma (PPARγ) is the transcription factor tha...

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Detalles Bibliográficos
Autores principales: Anagnostopoulos, Gerasimos, Motiño, Omar, Li, Sijing, Carbonnier, Vincent, Chen, Hui, Sica, Valentina, Durand, Sylvère, Bourgin, Mélanie, Aprahamian, Fanny, Nirmalathasan, Nitharsshini, Donne, Romain, Desdouets, Chantal, Sola, Marcelo Simon, Kotta, Konstantina, Montégut, Léa, Lambertucci, Flavia, Surdez, Didier, Sandrine, Grossetête, Delattre, Olivier, Maiuri, Maria Chiara, Bravo-San Pedro, José Manuel, Martins, Isabelle, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016078/
https://www.ncbi.nlm.nih.gov/pubmed/35436993
http://dx.doi.org/10.1038/s41419-022-04834-5

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