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Age-related visual impairments and retinal ganglion cells axonal degeneration in a mouse model harboring OPTN (E50K) mutation

Retinal ganglion cells (RGCs) axons are the signal carriers of visual information between retina and brain. Therefore, they play one of the important roles affected in many optic neurodegenerative diseases like glaucoma. Among the genetic risks associated with glaucoma, the E50K mutation in the Opti...

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Detalles Bibliográficos
Autores principales: Hou, Mingying, Shao, Zhengbo, Zhang, Shiqi, Liu, Xinna, Fan, Pan, Jiang, Menglu, Zhao, Yutong, Xiao, Rong, Yuan, Huiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016082/
https://www.ncbi.nlm.nih.gov/pubmed/35436991
http://dx.doi.org/10.1038/s41419-022-04836-3