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Age-related visual impairments and retinal ganglion cells axonal degeneration in a mouse model harboring OPTN (E50K) mutation
Retinal ganglion cells (RGCs) axons are the signal carriers of visual information between retina and brain. Therefore, they play one of the important roles affected in many optic neurodegenerative diseases like glaucoma. Among the genetic risks associated with glaucoma, the E50K mutation in the Opti...
Autores principales: | Hou, Mingying, Shao, Zhengbo, Zhang, Shiqi, Liu, Xinna, Fan, Pan, Jiang, Menglu, Zhao, Yutong, Xiao, Rong, Yuan, Huiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016082/ https://www.ncbi.nlm.nih.gov/pubmed/35436991 http://dx.doi.org/10.1038/s41419-022-04836-3 |
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