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The Associations of rs1799724 and rs361525 With the Risk of Ankylosing Spondylitis Are Dependent on HLA-B27 Status in a Chinese Han Population

OBJECTIVES: Human leucocyte antigen B27 (HLA-B27) is an important biomarker for ankylosing spondylitis (AS). However, delay in the diagnosis of AS is still common in clinical practice. Several single nucleotide polymorphisms (SNPs) in the coding gene of tumor necrosis factor alpha (TNFα) have been r...

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Detalles Bibliográficos
Autores principales: Sheng, Nan, Gao, Yingying, Li, Hui, Wang, Wenwen, Geng, Linyu, Zhang, Bo, Huang, Qiang, Wang, Xueqin, Sun, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016113/
https://www.ncbi.nlm.nih.gov/pubmed/35450075
http://dx.doi.org/10.3389/fimmu.2022.852326