Identification of novel small-molecular inhibitors of Staphylococcus aureus sortase A using hybrid virtual screening

Staphylococcus aureus is one of the most dangerous pathogens commonly associated with high levels of morbidity and mortality. Sortase A is considered as a promising molecular target for the development of antistaphylococcal agents. Using hybrid virtual screening approach and FRET analysis, we have i...

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Detalles Bibliográficos
Autores principales: Volynets, Galyna P., Barthels, Fabian, Hammerschmidt, Stefan J., Moshynets, Olena V., Lukashov, Sergiy S., Starosyla, Sergiy A., Vyshniakova, Hanna V., Iungin, Olga S., Bdzhola, Volodymyr G., Prykhod’ko, Andrii O., Syniugin, Anatolii R., Sapelkin, Vladislav M., Yarmoluk, Sergiy M., Schirmeister, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016125/
https://www.ncbi.nlm.nih.gov/pubmed/35440771
http://dx.doi.org/10.1038/s41429-022-00524-8

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