α-Amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor and RNA processing gene dysregulation are early determinants of selective motor neuron vulnerability in a mouse model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis is a late-onset adult neurodegenerative disease, although there is mounting electrophysiological and pathological evidence from patients and animal models for a protracted preclinical period of motor neuron susceptibility and dysfunction, long before clinical diagnosis....

Descripción completa

Detalles Bibliográficos
Autores principales: Zanganeh, Pardis F., Barton, Samantha K., Lim, Katherine, Qian, Elizabeth L., Crombie, Duncan E., Bye, Christopher R., Turner, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016138/
https://www.ncbi.nlm.nih.gov/pubmed/35445192
http://dx.doi.org/10.1093/braincomms/fcac081

Ejemplares similares

Ejemplares similares