Pharmacokinetic Herb-Drug Interactions of Xiang-Sha-Liu-Jun-Zi-Tang and Paclitaxel in Male Sprague Dawley Rats and Its Influence on Enzyme Kinetics in Human Liver Microsomes

Paclitaxel is a prescribed anticancer drug used to treat various cancers. It is a substrate of cytochrome P-450 (CYP-450) enzymes. Despite its efficacy, paclitaxel has severe side effects. Herbal medicines are commonly used to treat the side effects of chemotherapy. They can be administered before,...

Descripción completa

Detalles Bibliográficos
Autores principales: Kapelemera, Alinafe Magret, Uang, Yow-Shieng, Wang, Li-Hsuan, Wu, Tien-Yuan, Lee, Fang-Yu, Tai, Li, Wang, Ching-Chiung, Lee, Chia-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016196/
https://www.ncbi.nlm.nih.gov/pubmed/35450043
http://dx.doi.org/10.3389/fphar.2022.858007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016196/
https://www.ncbi.nlm.nih.gov/pubmed/35450043
http://dx.doi.org/10.3389/fphar.2022.858007

Ejemplares similares