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Pharmacokinetic Herb-Drug Interactions of Xiang-Sha-Liu-Jun-Zi-Tang and Paclitaxel in Male Sprague Dawley Rats and Its Influence on Enzyme Kinetics in Human Liver Microsomes

Paclitaxel is a prescribed anticancer drug used to treat various cancers. It is a substrate of cytochrome P-450 (CYP-450) enzymes. Despite its efficacy, paclitaxel has severe side effects. Herbal medicines are commonly used to treat the side effects of chemotherapy. They can be administered before,...

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Detalles Bibliográficos
Autores principales:	Kapelemera, Alinafe Magret, Uang, Yow-Shieng, Wang, Li-Hsuan, Wu, Tien-Yuan, Lee, Fang-Yu, Tai, Li, Wang, Ching-Chiung, Lee, Chia-Jung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016196/ https://www.ncbi.nlm.nih.gov/pubmed/35450043 http://dx.doi.org/10.3389/fphar.2022.858007

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