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Evolution of HLA-B Pharmacogenomics and the Importance of PGx Data Integration in Health Care System: A 10 Years Retrospective Study in Thailand

Background: The HLA-B is the most polymorphic gene, play a crucial role in drug-induced hypersensitivity reactions. There is a lot of evidence associating several risk alleles to life-threatening adverse drug reactions, and a few of them have been approved as valid biomarkers for predicting life-thr...

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Detalles Bibliográficos
Autores principales:	Koomdee, Napatrupron, Kloypan, Chiraphat, Jinda, Pimonpan, Rachanakul, Jiratha, Jantararoungtong, Thawinee, Sukprasong, Rattanaporn, Prommas, Santirhat, Nuntharadthanaphong, Nutthan, Puangpetch, Apichaya, Ershadian, Maliheh, John, Shobana, Biswas, Mohitosh, Sukasem, Chonlaphat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016335/ https://www.ncbi.nlm.nih.gov/pubmed/35450046 http://dx.doi.org/10.3389/fphar.2022.866903

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