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Reduced ER–mitochondria connectivity promotes neuroblastoma multidrug resistance

Most cancer deaths result from progression of therapy resistant disease, yet our understanding of this phenotype is limited. Cancer therapies generate stress signals that act upon mitochondria to initiate apoptosis. Mitochondria isolated from neuroblastoma cells were exposed to tBid or Bim, death ef...

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Detalles Bibliográficos
Autores principales:	Çoku, Jorida, Booth, David M, Skoda, Jan, Pedrotty, Madison C, Vogel, Jennifer, Liu, Kangning, Vu, Annette, Carpenter, Erica L, Ye, Jamie C, Chen, Michelle A, Dunbar, Peter, Scadden, Elizabeth, Yun, Taekyung D, Nakamaru‐Ogiso, Eiko, Area‐Gomez, Estela, Li, Yimei, Goldsmith, Kelly C, Reynolds, C Patrick, Hajnoczky, Gyorgy, Hogarty, Michael D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016347/ https://www.ncbi.nlm.nih.gov/pubmed/35211994 http://dx.doi.org/10.15252/embj.2021108272

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