DRP1 interacts directly with BAX to induce its activation and apoptosis

The apoptotic executioner protein BAX and the dynamin‐like protein DRP1 co‐localize at mitochondria during apoptosis to mediate mitochondrial permeabilization and fragmentation. However, the molecular basis and functional consequences of this interplay remain unknown. Here, we show that BAX and DRP1...

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Detalles Bibliográficos
Autores principales: Jenner, Andreas, Peña‐Blanco, Aida, Salvador‐Gallego, Raquel, Ugarte‐Uribe, Begoña, Zollo, Cristiana, Ganief, Tariq, Bierlmeier, Jan, Mund, Markus, Lee, Jason E, Ries, Jonas, Schwarzer, Dirk, Macek, Boris, Garcia‐Saez, Ana J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016351/
https://www.ncbi.nlm.nih.gov/pubmed/35023587
http://dx.doi.org/10.15252/embj.2021108587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016351/
https://www.ncbi.nlm.nih.gov/pubmed/35023587
http://dx.doi.org/10.15252/embj.2021108587

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