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DRP1 interacts directly with BAX to induce its activation and apoptosis
The apoptotic executioner protein BAX and the dynamin‐like protein DRP1 co‐localize at mitochondria during apoptosis to mediate mitochondrial permeabilization and fragmentation. However, the molecular basis and functional consequences of this interplay remain unknown. Here, we show that BAX and DRP1...
Autores principales: | Jenner, Andreas, Peña‐Blanco, Aida, Salvador‐Gallego, Raquel, Ugarte‐Uribe, Begoña, Zollo, Cristiana, Ganief, Tariq, Bierlmeier, Jan, Mund, Markus, Lee, Jason E, Ries, Jonas, Schwarzer, Dirk, Macek, Boris, Garcia‐Saez, Ana J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016351/ https://www.ncbi.nlm.nih.gov/pubmed/35023587 http://dx.doi.org/10.15252/embj.2021108587 |
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