Vaccination With Detoxified Leukocidin AB Reduces Bacterial Load in a Staphylococcus aureus Minipig Deep Surgical Wound Infection Model

Vaccines against Staphylococcus aureus have eluded researchers for >3 decades while the burden of staphylococcal diseases has increased. Early vaccine attempts mainly used rodents to characterize preclinical efficacy, and all subsequently failed in human clinical efficacy trials. More recently, l...

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Detalles Bibliográficos
Autores principales: Fernandez, Jeffrey, Sanders, Holly, Henn, Jessica, Wilson, Jolaine M, Malone, Danielle, Buoninfante, Alessandra, Willms, Matthew, Chan, Rita, DuMont, Ashley L, McLahan, Craig, Grubb, Kaitlyn, Romanello, Anthony, van den Dobbelsteen, Germie, Torres, Victor J, Poolman, Jan T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016470/
https://www.ncbi.nlm.nih.gov/pubmed/33895843
http://dx.doi.org/10.1093/infdis/jiab219

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