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The histone variant macroH2A1.1 regulates RNA polymerase II-paused genes within defined chromatin interaction landscapes

The histone variant macroH2A1.1 plays a role in cancer development and metastasis. To determine the underlying molecular mechanisms, we mapped the genome-wide localization of endogenous macroH2A1.1 in the human breast cancer cell line MDA-MB-231. We demonstrate that macroH2A1.1 specifically binds to...

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Detalles Bibliográficos
Autores principales:	Recoules, Ludmila, Heurteau, Alexandre, Raynal, Flavien, Karasu, Nezih, Moutahir, Fatima, Bejjani, Fabienne, Jariel-Encontre, Isabelle, Cuvier, Olivier, Sexton, Thomas, Lavigne, Anne-Claire, Bystricky, Kerstin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016624/ https://www.ncbi.nlm.nih.gov/pubmed/35362516 http://dx.doi.org/10.1242/jcs.259456

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