Broadly neutralizing antibodies target the coronavirus fusion peptide

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The potential for future coronavirus outbreaks highlights the need to develop strategies and tools to broadly target this group of pathogens. Here, using an epitope-agnostic approach, we identified six monoclonal antibodies that bound to spike proteins from all seven human-infecting coronaviruses. E...

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Detalles Bibliográficos
Autores principales: Dacon, Cherrelle, Tucker, Courtney, Peng, Linghang, Lee, Chang-Chun D., Lin, Ting-Hui, Yuan, Meng, Cong, Yu, Wang, Lingshu, Purser, Lauren, Williams, Jazmean K., Pyo, Chul-Woo, Kosik, Ivan, Hu, Zhe, Zhao, Ming, Mohan, Divya, Cooper, Andrew, Peterson, Mary, Skinner, Jeff, Dixit, Saurabh, Kollins, Erin, Huzella, Louis, Perry, Donna, Byrum, Russell, Lembirik, Sanae, Zhang, Yi, Yang, Eun Sung, Chen, Man, Leung, Kwanyee, Weinberg, Rona S., Pegu, Amarendra, Geraghty, Daniel E., Davidson, Edgar, Douagi, Iyadh, Moir, Susan, Yewdell, Jonathan W., Schmaljohn, Connie, Crompton, Peter D., Holbrook, Michael R., Nemazee, David, Mascola, John R., Wilson, Ian A., Tan, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016638/
https://www.ncbi.nlm.nih.gov/pubmed/35441178
http://dx.doi.org/10.1101/2022.04.11.487879
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