Genome wide screen of RNAi molecules against SARS-CoV-2 creates a broadly potent prophylaxis

Expanding the arsenal of prophylactic approaches against SARS-CoV-2 is of utmost importance, specifically those strategies that are resistant to antigenic drift in Spike. Here, we conducted a screen with over 16,000 RNAi triggers against the SARS-CoV-2 genome using a massively parallel assay to iden...

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Detalles Bibliográficos
Autores principales: Yogev, Ohad, Weissbrod, Omer, Battistoni, Giorgia, Bressan, Dario, Naamti, Adi, Falciatori, Ilaria, Berkyurek, Ahmet C., Rasnic, Roni, Hosmillo, Myra, Ilan, Shaul, Grossman, Iris, McCormick, Lauren, Honeycutt, Christopher C., Johnston, Timothy, Gagne, Matthew, Douek, Daniel C., Goodfellow, Ian, Hannon, Gregory J., Erlich, Yaniv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016640/
https://www.ncbi.nlm.nih.gov/pubmed/35441162
http://dx.doi.org/10.1101/2022.04.12.488010

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