Receptor binding domain of SARS-CoV-2 is a functional αv-integrin agonist

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Among the novel mutations distinguishing SARS-CoV-2 from similar respiratory coronaviruses is a K403R substitution in the receptor-binding domain (RBD) of the viral spike (S) protein within its S1 region. This amino acid substitution occurs near the angiotensin-converting enzyme 2 (ACE2)-binding int...

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Detalles Bibliográficos
Autores principales: Norris, Emma G., Pan, Xuan Sabrina, Hocking, Denise C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016641/
https://www.ncbi.nlm.nih.gov/pubmed/35441172
http://dx.doi.org/10.1101/2022.04.11.487882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016641/
https://www.ncbi.nlm.nih.gov/pubmed/35441172
http://dx.doi.org/10.1101/2022.04.11.487882

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