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Famotidine activates the vagus nerve inflammatory reflex to attenuate cytokine storm

BACKGROUND. Severe COVID-19 is characterized by pro-inflammatory cytokine release syndrome (cytokine storm) which causes high morbidity and mortality. Recent observational and clinical studies suggest famotidine, a histamine 2 receptor (H2R) antagonist widely used to treat gastroesophageal reflux di...

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Detalles Bibliográficos
Autores principales: yang, huan, George, Sam J, Thompson, Dane, Silverman, Harold A, Tsaava, Tea, Tynan, Aisling, Pavlov, Valentin A, Chang, Eric, Andersson, Ulf, Brines, Michael, Chavan, Sangeeta S, Tracey, Kevin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016653/
https://www.ncbi.nlm.nih.gov/pubmed/35441176
http://dx.doi.org/10.21203/rs.3.rs-1493296/v1