Notch1-CD22-Dependent Immune Dysregulation in the SARS-CoV2-Associated Multisystem Inflammatory Syndrome in Children

Multisystem inflammatory syndrome in children (MIS-C) evolves in some pediatric patients following acute infection with SARS-CoV-2 by hitherto unknown mechanisms. Whereas acute-COVID-19 severity and outcome were previously correlated with Notch4 expression on regulatory T (Treg) cells, here we show...

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Autores principales: Chatila, Talal A., Benamar, Mehdi, Chen, Qian, Chou, Janet, Julé, Amelie, Boudra, Rafik, Contini, Paola, Crestani, Elena, Wang, Muyun, Fong, Jason, Lai, Peggy, Rockwitz, Shira, Lee, Pui, Chan, Tsz Man Fion, Altun, Ekin Zeynep, Kepenekli, Eda, Karakoc-Aydiner, Elif, Ozen, Ahmet, Boran, Perran, Aygun, Fatih, Onal, Pinar, Sakalli, Ayse Ayzit Kilinc, Cokugras, Haluk, Gelmez, Metin, Öktelik, Fatma, Cetin, Esin Aktaş, Zhong, Yuelin, Taylor, Maria, Irby, Katherine, Halasa, Natasha, Signa, Sara, Prigione, Ignazia, Gattorno, Marco, Cotugno, Nicola, Amodio, Donato, Geha, Raif, Son, Mary Beth, Newburger, Jane, Agrawal, Pankaj, Volpi, Stefano, Palma, Paolo, Kiykim, Ayca, Randolph, Adrienne, Deniz, Gunnur, Baris, Safa, De Palma, Raffaele, Schmitz-Abe, Klaus, Charbonnier, Louis-Marie, Henderson, Lauren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016654/
https://www.ncbi.nlm.nih.gov/pubmed/35441180
http://dx.doi.org/10.21203/rs.3.rs-1054453/v1

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