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Novel adamantyl clubbed iminothiazolidinones as promising elastase inhibitors: design, synthesis, molecular docking, ADMET and DFT studies

Porcine Pancreatic Elastase (PPE) is a serine protease that is homologous to trypsin and chymotrypsin that are involved in various pathologies like inflammatory disease, Chronic Obstructive Pulmonary Disease (COPD), acute respiratory distress syndrome, cystic fibrosis, and atherosclerosis. PPE if re...

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Detalles Bibliográficos
Autores principales:	Ahmed, Atteeque, Saeed, Aamer, Ejaz, Syeda Abida, Aziz, Mubashir, Hashmi, Muhammad Zaffar, Channar, Pervaiz Ali, Abbas, Qamar, Raza, Hussain, Shafiq, Zahid, El-Seedi, Hesham R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016748/ https://www.ncbi.nlm.nih.gov/pubmed/35481107 http://dx.doi.org/10.1039/d1ra09318e

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