Molecular Recognition in an Aqueous Medium Using Water-Soluble Prismarene Hosts

[Image: see text] The synthesis of water-soluble prism[n]arenes (n = 5 and 6) bearing anionic carboxylato groups on the rims is described. The binding properties of this novel class of water-soluble hosts are studied by nuclear magnetic resonance and calorimetry. The complexation of singly and doubl...

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Autores principales: Del Regno, Rocco, Santonoceta, Giuseppina D. G., Della Sala, Paolo, De Rosa, Margherita, Soriente, Annunziata, Talotta, Carmen, Spinella, Aldo, Neri, Placido, Sgarlata, Carmelo, Gaeta, Carmine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016763/
https://www.ncbi.nlm.nih.gov/pubmed/35389649
http://dx.doi.org/10.1021/acs.orglett.2c00819
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author Del Regno, Rocco
Santonoceta, Giuseppina D. G.
Della Sala, Paolo
De Rosa, Margherita
Soriente, Annunziata
Talotta, Carmen
Spinella, Aldo
Neri, Placido
Sgarlata, Carmelo
Gaeta, Carmine
author_facet Del Regno, Rocco
Santonoceta, Giuseppina D. G.
Della Sala, Paolo
De Rosa, Margherita
Soriente, Annunziata
Talotta, Carmen
Spinella, Aldo
Neri, Placido
Sgarlata, Carmelo
Gaeta, Carmine
author_sort Del Regno, Rocco
collection PubMed
description [Image: see text] The synthesis of water-soluble prism[n]arenes (n = 5 and 6) bearing anionic carboxylato groups on the rims is described. The binding properties of this novel class of water-soluble hosts are studied by nuclear magnetic resonance and calorimetry. The complexation of singly and doubly charged ammonium guests with the more rigid pentamer is enthalpically driven by secondary interactions, while the thermodynamic fingerprint for the larger hexamer reveals driving forces that strongly depend on the guest charge and/or size.
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spelling pubmed-90167632022-04-20 Molecular Recognition in an Aqueous Medium Using Water-Soluble Prismarene Hosts Del Regno, Rocco Santonoceta, Giuseppina D. G. Della Sala, Paolo De Rosa, Margherita Soriente, Annunziata Talotta, Carmen Spinella, Aldo Neri, Placido Sgarlata, Carmelo Gaeta, Carmine Org Lett [Image: see text] The synthesis of water-soluble prism[n]arenes (n = 5 and 6) bearing anionic carboxylato groups on the rims is described. The binding properties of this novel class of water-soluble hosts are studied by nuclear magnetic resonance and calorimetry. The complexation of singly and doubly charged ammonium guests with the more rigid pentamer is enthalpically driven by secondary interactions, while the thermodynamic fingerprint for the larger hexamer reveals driving forces that strongly depend on the guest charge and/or size. American Chemical Society 2022-04-07 2022-04-15 /pmc/articles/PMC9016763/ /pubmed/35389649 http://dx.doi.org/10.1021/acs.orglett.2c00819 Text en © 2022 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Del Regno, Rocco
Santonoceta, Giuseppina D. G.
Della Sala, Paolo
De Rosa, Margherita
Soriente, Annunziata
Talotta, Carmen
Spinella, Aldo
Neri, Placido
Sgarlata, Carmelo
Gaeta, Carmine
Molecular Recognition in an Aqueous Medium Using Water-Soluble Prismarene Hosts
title Molecular Recognition in an Aqueous Medium Using Water-Soluble Prismarene Hosts
title_full Molecular Recognition in an Aqueous Medium Using Water-Soluble Prismarene Hosts
title_fullStr Molecular Recognition in an Aqueous Medium Using Water-Soluble Prismarene Hosts
title_full_unstemmed Molecular Recognition in an Aqueous Medium Using Water-Soluble Prismarene Hosts
title_short Molecular Recognition in an Aqueous Medium Using Water-Soluble Prismarene Hosts
title_sort molecular recognition in an aqueous medium using water-soluble prismarene hosts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016763/
https://www.ncbi.nlm.nih.gov/pubmed/35389649
http://dx.doi.org/10.1021/acs.orglett.2c00819
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