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Fatty Acid Substitutions Modulate the Cytotoxicity of Puwainaphycins/Minutissamides Isolated from the Baltic Sea Cyanobacterium Nodularia harveyana UHCC-0300

[Image: see text] Puwainaphycins (PUW) and minutissamides (MIN) are structurally homologous cyclic lipopeptides that exhibit high structural variability and possess antifungal and cytotoxic activities. While only a minor variation can be found in the amino acid composition of the peptide cycle, the...

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Detalles Bibliográficos
Autores principales:	Saurav, Kumar, Caso, Alessia, Urajová, Petra, Hrouzek, Pavel, Esposito, Germana, Delawská, Kateřina, Macho, Markéta, Hájek, Jan, Cheel, José, Saha, Subhasish, Divoká, Petra, Arsin, Sila, Sivonen, Kaarina, Fewer, David P., Costantino, Valeria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016887/ https://www.ncbi.nlm.nih.gov/pubmed/35449984 http://dx.doi.org/10.1021/acsomega.1c07160

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