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Memantine-Derived Schiff Bases as Transdermal Prodrug Candidates

[Image: see text] Condensation reactions of salicylaldehyde, 2-pyridinecarboxaldehyde, and pyridoxaldehyde with memantine (Me) produced novel memantine-derived Schiff bases (1–3). Speciation predictions and calculations of Log P, Log D, and of the percentage (%) of neutral species for (1–3) were car...

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Detalles Bibliográficos
Autores principales:	Araujo de Oliveira, Ana P., Romero Colmenares, Victoria C., Diniz, Renata, Freitas, Jennifer T. J., da Cruz, Clara M., Lages, Eduardo B., Ferreira, Lucas A. M., Vieira, Rafael P., Beraldo, Heloisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017104/ https://www.ncbi.nlm.nih.gov/pubmed/35449959 http://dx.doi.org/10.1021/acsomega.1c06571

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