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Interrogating RNA and protein spatial subcellular distribution in smFISH data with DypFISH

Advances in single-cell RNA sequencing have allowed for the identification of cellular subtypes on the basis of quantification of the number of transcripts in each cell. However, cells might also differ in the spatial distribution of molecules, including RNAs. Here, we present DypFISH, an approach t...

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Detalles Bibliográficos
Autores principales: Savulescu, Anca F., Brackin, Robyn, Bouilhol, Emmanuel, Dartigues, Benjamin, Warrell, Jonathan H., Pimentel, Mafalda R., Beaume, Nicolas, Fortunato, Isabela C., Dallongeville, Stephane, Boulle, Mikaël, Soueidan, Hayssam, Agou, Fabrice, Schmoranzer, Jan, Olivo-Marin, Jean-Christophe, Franco, Claudio A., Gomes, Edgar R., Nikolski, Macha, Mhlanga, Musa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017151/
https://www.ncbi.nlm.nih.gov/pubmed/35474672
http://dx.doi.org/10.1016/j.crmeth.2021.100068