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A multidimensional HIV-1 persistence model for clonal expansion and viral rebound in vitro
Using a replication-competent virus for prolonged in vitro culture, Matsuda et al. captured the heterogenous HIV-1 genome and integration site landscape, examined viral cytopathic effects and clonal expansion capacity, and tested drugs that can eliminate HIV-1-infected cells.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017154/ https://www.ncbi.nlm.nih.gov/pubmed/35475216 http://dx.doi.org/10.1016/j.crmeth.2021.100134 |
| _version_ | 1784688719808167936 |
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| author | Eshetu, Amare Ho, Ya-Chi |
| author_facet | Eshetu, Amare Ho, Ya-Chi |
| author_sort | Eshetu, Amare |
| collection | PubMed |
| description | Using a replication-competent virus for prolonged in vitro culture, Matsuda et al. captured the heterogenous HIV-1 genome and integration site landscape, examined viral cytopathic effects and clonal expansion capacity, and tested drugs that can eliminate HIV-1-infected cells. |
| format | Online Article Text |
| id | pubmed-9017154 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-90171542022-04-25 A multidimensional HIV-1 persistence model for clonal expansion and viral rebound in vitro Eshetu, Amare Ho, Ya-Chi Cell Rep Methods Preview Using a replication-competent virus for prolonged in vitro culture, Matsuda et al. captured the heterogenous HIV-1 genome and integration site landscape, examined viral cytopathic effects and clonal expansion capacity, and tested drugs that can eliminate HIV-1-infected cells. Elsevier 2021-12-20 /pmc/articles/PMC9017154/ /pubmed/35475216 http://dx.doi.org/10.1016/j.crmeth.2021.100134 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Preview Eshetu, Amare Ho, Ya-Chi A multidimensional HIV-1 persistence model for clonal expansion and viral rebound in vitro |
| title | A multidimensional HIV-1 persistence model for clonal expansion and viral rebound in vitro |
| title_full | A multidimensional HIV-1 persistence model for clonal expansion and viral rebound in vitro |
| title_fullStr | A multidimensional HIV-1 persistence model for clonal expansion and viral rebound in vitro |
| title_full_unstemmed | A multidimensional HIV-1 persistence model for clonal expansion and viral rebound in vitro |
| title_short | A multidimensional HIV-1 persistence model for clonal expansion and viral rebound in vitro |
| title_sort | multidimensional hiv-1 persistence model for clonal expansion and viral rebound in vitro |
| topic | Preview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017154/ https://www.ncbi.nlm.nih.gov/pubmed/35475216 http://dx.doi.org/10.1016/j.crmeth.2021.100134 |
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