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A multidimensional HIV-1 persistence model for clonal expansion and viral rebound in vitro
Using a replication-competent virus for prolonged in vitro culture, Matsuda et al. captured the heterogenous HIV-1 genome and integration site landscape, examined viral cytopathic effects and clonal expansion capacity, and tested drugs that can eliminate HIV-1-infected cells.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017154/ https://www.ncbi.nlm.nih.gov/pubmed/35475216 http://dx.doi.org/10.1016/j.crmeth.2021.100134 |