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PeakVI: A deep generative model for single-cell chromatin accessibility analysis

Single-cell ATAC sequencing (scATAC-seq) is a powerful and increasingly popular technique to explore the regulatory landscape of heterogeneous cellular populations. However, the high noise levels, degree of sparsity, and scale of the generated data make its analysis challenging. Here, we present Pea...

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Detalles Bibliográficos
Autores principales: Ashuach, Tal, Reidenbach, Daniel A., Gayoso, Adam, Yosef, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017241/
https://www.ncbi.nlm.nih.gov/pubmed/35475224
http://dx.doi.org/10.1016/j.crmeth.2022.100182