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mtDNA-STING Axis Mediates Microglial Polarization via IRF3/NF-κB Signaling After Ischemic Stroke

Neuroinflammation is initiated in response to ischemic stroke, and is usually characterized by microglial activation and polarization. Stimulator of interferon genes (STING) has been shown to play a critical role in anti-tumor immunity and inflammatory diseases. Nevertheless, the effect and underlyi...

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Detalles Bibliográficos
Autores principales:	Kong, Lingqi, Li, Wenyu, Chang, E, Wang, Wuxuan, Shen, Nan, Xu, Xiang, Wang, Xinyue, Zhang, Yan, Sun, Wen, Hu, Wei, Xu, Pengfei, Liu, Xinfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017276/ https://www.ncbi.nlm.nih.gov/pubmed/35450066 http://dx.doi.org/10.3389/fimmu.2022.860977

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