An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses

The devastation caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made clear the importance of pandemic preparedness. To address future zoonotic outbreaks due to related viruses in the sarbecovirus subgenus, we identified a human monoclonal antibody, 10-40, that neutralized...

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Detalles Bibliográficos
Autores principales: Liu, Lihong, Iketani, Sho, Guo, Yicheng, Casner, Ryan G., Reddem, Eswar R., Nair, Manoj S., Yu, Jian, Chan, Jasper F-W., Wang, Maple, Cerutti, Gabriele, Li, Zhiteng, Morano, Nicholas C., Castagna, Candace D., Corredor, Laura, Chu, Hin, Yuan, Shuofeng, Poon, Vincent Kwok-Man, Chan, Chris Chun-Sing, Chen, Zhiwei, Luo, Yang, Cunningham, Marcus, Chavez, Alejandro, Yin, Michael T., Perlin, David S., Tsuji, Moriya, Yuen, Kwok-Yung, Kwong, Peter D., Sheng, Zizhang, Huang, Yaoxing, Shapiro, Lawrence, Ho, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017343/
https://www.ncbi.nlm.nih.gov/pubmed/35438546
http://dx.doi.org/10.1126/scitranslmed.abn6859

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