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Monoclonal Antibodies Targeting Surface-Exposed Epitopes of Candida albicans Cell Wall Proteins Confer In Vivo Protection in an Infection Model
Monoclonal antibody (mAb)-based immunotherapies targeting systemic and deep-seated fungal infections are still in their early stages of development, with no licensed antifungal mAbs currently being available for patients at risk. The cell wall glycoproteins of Candida albicans are of particular inte...
Autores principales: | Palliyil, Soumya, Mawer, Mark, Alawfi, Sami A., Fogg, Lily, Tan, Tyng H., De Cesare, Giuseppe Buda, Walker, Louise A., MacCallum, Donna M., Porter, Andrew J., Munro, Carol A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017365/ https://www.ncbi.nlm.nih.gov/pubmed/35285676 http://dx.doi.org/10.1128/aac.01957-21 |
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