Cargando…

A longitudinal cohort study of gestational diabetes mellitus and perinatal depression

BACKGROUND: The association between gestational diabetes mellitus (GDM) and perinatal depression (PND) remains controversial. Our study aimed to comprehensively assess this association in a longitudinal cohort study with repeated measurements of depression. METHODS: Our cohort study was nested in a...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Haiyan, Yu, Xiayan, Qiang, Wenjing, Lu, Mengjuan, Jiang, Minmin, Hou, Yanyan, Gu, Yue, Tao, Fangbiao, Zhu, Beibei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017412/
https://www.ncbi.nlm.nih.gov/pubmed/35440070
http://dx.doi.org/10.1186/s12884-022-04667-2
_version_ 1784688755610746880
author Li, Haiyan
Yu, Xiayan
Qiang, Wenjing
Lu, Mengjuan
Jiang, Minmin
Hou, Yanyan
Gu, Yue
Tao, Fangbiao
Zhu, Beibei
author_facet Li, Haiyan
Yu, Xiayan
Qiang, Wenjing
Lu, Mengjuan
Jiang, Minmin
Hou, Yanyan
Gu, Yue
Tao, Fangbiao
Zhu, Beibei
author_sort Li, Haiyan
collection PubMed
description BACKGROUND: The association between gestational diabetes mellitus (GDM) and perinatal depression (PND) remains controversial. Our study aimed to comprehensively assess this association in a longitudinal cohort study with repeated measurements of depression. METHODS: Our cohort study was nested in a pilot study of an implementation study aiming to screen and manage perinatal depression within the primary health system in China. Women were recruited in the first trimester from May–September 2019 and followed four times up to 1 year postpartum. Data on sociodemographic characteristics and depression were collected using self-developed questionnaires incorporating the Edinburgh Postnatal Depression Scale (EPDS). Oral glucose tolerance test at 24 ~ 28 weeks and fasting plasma glucose (FPG) data were extracted from medical records. Depression throughout the whole period was divided into different trajectories. Associations of GDM with PND at different time periods and PND of different trajectories were determined by logistic regression. The path of association between blood glucose and depression over time was estimated with an autoregressive cross-lagged model. RESULTS: In total, 1043 women were included in this analysis and 313 (30.0%) were diagnosed with GDM. The prevalence of depression in the first, second, and third trimesters and postpartum period were 17.2, 6.9, 6.8 and 9.0%, respectively. GDM was neither significantly associated with PND at any time point nor with any specific trajectory of depression. Except for autoregressive paths, no cross-lagged path of FPG and scores of EPDS was significant. CONCLUSIONS: Our study indicates no association between GDM/blood glucose and PND. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12884-022-04667-2.
format Online
Article
Text
id pubmed-9017412
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-90174122022-04-19 A longitudinal cohort study of gestational diabetes mellitus and perinatal depression Li, Haiyan Yu, Xiayan Qiang, Wenjing Lu, Mengjuan Jiang, Minmin Hou, Yanyan Gu, Yue Tao, Fangbiao Zhu, Beibei BMC Pregnancy Childbirth Research Article BACKGROUND: The association between gestational diabetes mellitus (GDM) and perinatal depression (PND) remains controversial. Our study aimed to comprehensively assess this association in a longitudinal cohort study with repeated measurements of depression. METHODS: Our cohort study was nested in a pilot study of an implementation study aiming to screen and manage perinatal depression within the primary health system in China. Women were recruited in the first trimester from May–September 2019 and followed four times up to 1 year postpartum. Data on sociodemographic characteristics and depression were collected using self-developed questionnaires incorporating the Edinburgh Postnatal Depression Scale (EPDS). Oral glucose tolerance test at 24 ~ 28 weeks and fasting plasma glucose (FPG) data were extracted from medical records. Depression throughout the whole period was divided into different trajectories. Associations of GDM with PND at different time periods and PND of different trajectories were determined by logistic regression. The path of association between blood glucose and depression over time was estimated with an autoregressive cross-lagged model. RESULTS: In total, 1043 women were included in this analysis and 313 (30.0%) were diagnosed with GDM. The prevalence of depression in the first, second, and third trimesters and postpartum period were 17.2, 6.9, 6.8 and 9.0%, respectively. GDM was neither significantly associated with PND at any time point nor with any specific trajectory of depression. Except for autoregressive paths, no cross-lagged path of FPG and scores of EPDS was significant. CONCLUSIONS: Our study indicates no association between GDM/blood glucose and PND. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12884-022-04667-2. BioMed Central 2022-04-19 /pmc/articles/PMC9017412/ /pubmed/35440070 http://dx.doi.org/10.1186/s12884-022-04667-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Li, Haiyan
Yu, Xiayan
Qiang, Wenjing
Lu, Mengjuan
Jiang, Minmin
Hou, Yanyan
Gu, Yue
Tao, Fangbiao
Zhu, Beibei
A longitudinal cohort study of gestational diabetes mellitus and perinatal depression
title A longitudinal cohort study of gestational diabetes mellitus and perinatal depression
title_full A longitudinal cohort study of gestational diabetes mellitus and perinatal depression
title_fullStr A longitudinal cohort study of gestational diabetes mellitus and perinatal depression
title_full_unstemmed A longitudinal cohort study of gestational diabetes mellitus and perinatal depression
title_short A longitudinal cohort study of gestational diabetes mellitus and perinatal depression
title_sort longitudinal cohort study of gestational diabetes mellitus and perinatal depression
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017412/
https://www.ncbi.nlm.nih.gov/pubmed/35440070
http://dx.doi.org/10.1186/s12884-022-04667-2
work_keys_str_mv AT lihaiyan alongitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT yuxiayan alongitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT qiangwenjing alongitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT lumengjuan alongitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT jiangminmin alongitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT houyanyan alongitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT guyue alongitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT taofangbiao alongitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT zhubeibei alongitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT lihaiyan longitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT yuxiayan longitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT qiangwenjing longitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT lumengjuan longitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT jiangminmin longitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT houyanyan longitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT guyue longitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT taofangbiao longitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression
AT zhubeibei longitudinalcohortstudyofgestationaldiabetesmellitusandperinataldepression