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Counteranions at Peripheral Sites Tune Guest Affinity for a Protonated Hemicryptophane
[Image: see text] The affinity of small molecules for biomolecular cavities is tuned through a combination of primary and secondary interactions. It has been challenging to mimic these features in organic synthetic host molecules, however, where the cavities tend to be highly symmetric and nonpolar,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017572/ https://www.ncbi.nlm.nih.gov/pubmed/35333529 http://dx.doi.org/10.1021/acs.joc.1c03128 |