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Smad2 inhibition of MET transcription potentiates human vascular smooth muscle cell apoptosis

BACKGROUND: Vascular smooth muscle cell (SMC) apoptosis is involved in major cardiovascular diseases. Smad2 is a transcription factor implicated in aortic aneurysm. The molecular mediators of Smad2-driven SMC apoptosis are not well defined. Here we have identified a Smad2-directed mechanism involvin...

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Detalles Bibliográficos
Autores principales:	Xie, Xiujie, Shirasu, Takuro, Guo, Lian-Wang, Kent, K. Craig
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017589/ https://www.ncbi.nlm.nih.gov/pubmed/35445204 http://dx.doi.org/10.1016/j.athplu.2021.08.005

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