Research following genome‐wide association study focuses on the multifaceted nature of Src kinase‐associated phosphoprotein 2 in type 1 diabetes

Rutsch et al. identified a patient with type 1 diabetes having a rare Src kinase‐associated phosphoprotein 2 variant and investigated the details. As a result, they showed that rare Src kinase‐associated phosphoprotein 2 c.475 G>A increases macrophage activity and promotes type 1 diabetes, as wel...

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Detalles Bibliográficos
Autores principales: Sano, Hiroyuki, Imagawa, Akihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017624/
https://www.ncbi.nlm.nih.gov/pubmed/34989154
http://dx.doi.org/10.1111/jdi.13744
Descripción
Sumario:Rutsch et al. identified a patient with type 1 diabetes having a rare Src kinase‐associated phosphoprotein 2 variant and investigated the details. As a result, they showed that rare Src kinase‐associated phosphoprotein 2 c.475 G>A increases macrophage activity and promotes type 1 diabetes, as well as autoimmune and inflammatory diseases.[Image: see text]

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