Research following genome‐wide association study focuses on the multifaceted nature of Src kinase‐associated phosphoprotein 2 in type 1 diabetes

Rutsch et al. identified a patient with type 1 diabetes having a rare Src kinase‐associated phosphoprotein 2 variant and investigated the details. As a result, they showed that rare Src kinase‐associated phosphoprotein 2 c.475 G>A increases macrophage activity and promotes type 1 diabetes, as wel...

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Detalles Bibliográficos
Autores principales: Sano, Hiroyuki, Imagawa, Akihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017624/
https://www.ncbi.nlm.nih.gov/pubmed/34989154
http://dx.doi.org/10.1111/jdi.13744
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author Sano, Hiroyuki
Imagawa, Akihisa
author_facet Sano, Hiroyuki
Imagawa, Akihisa
author_sort Sano, Hiroyuki
collection PubMed
description Rutsch et al. identified a patient with type 1 diabetes having a rare Src kinase‐associated phosphoprotein 2 variant and investigated the details. As a result, they showed that rare Src kinase‐associated phosphoprotein 2 c.475 G>A increases macrophage activity and promotes type 1 diabetes, as well as autoimmune and inflammatory diseases.[Image: see text]
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spelling pubmed-90176242022-04-21 Research following genome‐wide association study focuses on the multifaceted nature of Src kinase‐associated phosphoprotein 2 in type 1 diabetes Sano, Hiroyuki Imagawa, Akihisa J Diabetes Investig Commentary Rutsch et al. identified a patient with type 1 diabetes having a rare Src kinase‐associated phosphoprotein 2 variant and investigated the details. As a result, they showed that rare Src kinase‐associated phosphoprotein 2 c.475 G>A increases macrophage activity and promotes type 1 diabetes, as well as autoimmune and inflammatory diseases.[Image: see text] John Wiley and Sons Inc. 2022-02-04 2022-04 /pmc/articles/PMC9017624/ /pubmed/34989154 http://dx.doi.org/10.1111/jdi.13744 Text en © 2022 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Commentary
Sano, Hiroyuki
Imagawa, Akihisa
Research following genome‐wide association study focuses on the multifaceted nature of Src kinase‐associated phosphoprotein 2 in type 1 diabetes
title Research following genome‐wide association study focuses on the multifaceted nature of Src kinase‐associated phosphoprotein 2 in type 1 diabetes
title_full Research following genome‐wide association study focuses on the multifaceted nature of Src kinase‐associated phosphoprotein 2 in type 1 diabetes
title_fullStr Research following genome‐wide association study focuses on the multifaceted nature of Src kinase‐associated phosphoprotein 2 in type 1 diabetes
title_full_unstemmed Research following genome‐wide association study focuses on the multifaceted nature of Src kinase‐associated phosphoprotein 2 in type 1 diabetes
title_short Research following genome‐wide association study focuses on the multifaceted nature of Src kinase‐associated phosphoprotein 2 in type 1 diabetes
title_sort research following genome‐wide association study focuses on the multifaceted nature of src kinase‐associated phosphoprotein 2 in type 1 diabetes
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017624/
https://www.ncbi.nlm.nih.gov/pubmed/34989154
http://dx.doi.org/10.1111/jdi.13744
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