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SMN-deficient cells exhibit increased ribosomal DNA damage

Spinal muscular atrophy, the leading genetic cause of infant mortality, is a motor neuron disease caused by low levels of survival motor neuron (SMN) protein. SMN is a multifunctional protein that is implicated in numerous cytoplasmic and nuclear processes. Recently, increasing attention is being pa...

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Detalles Bibliográficos
Autores principales:	Karyka, Evangelia, Berrueta Ramirez, Nelly, Webster, Christopher P, Marchi, Paolo M, Graves, Emily J, Godena, Vinay K, Marrone, Lara, Bhargava, Anushka, Ray, Swagat, Ning, Ke, Crane, Hannah, Hautbergue, Guillaume M, El-Khamisy, Sherif F, Azzouz, Mimoun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018017/ https://www.ncbi.nlm.nih.gov/pubmed/35440492 http://dx.doi.org/10.26508/lsa.202101145

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