Methaemoglobinemia after Liposuction under Tumescent Local Anaesthesia – Diagnostic Value of Pulse Oximetry

BACKGROUND: Tumescent local anaesthesia with prilocain can lead to clinically significant methemoglobin levels. New generation multiple wavelength pulse oximeters (e. g. Masimo Radical 7®) can measure methemoglobin levels. METHODS: In this prospective observational study we compared the venous methe...

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Detalles Bibliográficos
Autores principales: Brandt, Sebastian, Kimberger, Oliver, Weber, Benjamin, Klose, Anne, Stockmann, Swetlana, Schmeller, Wilfried, Gehring, Hartmut, Kellner, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society for Plastic Surgeons 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018037/
https://www.ncbi.nlm.nih.gov/pubmed/35592237
http://dx.doi.org/10.52547/wjps.11.1.111
Descripción
Sumario:BACKGROUND: Tumescent local anaesthesia with prilocain can lead to clinically significant methemoglobin levels. New generation multiple wavelength pulse oximeters (e. g. Masimo Radical 7®) can measure methemoglobin levels. METHODS: In this prospective observational study we compared the venous methemoglobin levels and the corresponding pulse oximetric values of the Radical 7® in patients undergoing tumescent local anaesthesia for liposuction procedures. The measurements were performed in Hanseklinik, Luebeck, Germany between 2008 and 2011. RESULTS: In 133 patients, we measured a maximum methemoglobin level of 18 per cent. In a Bland-Altman analysis we found a mean bias of +2.2 % (-4.1 to 8.4 limits of agreement) for pulse oximetric values compared to hemoximetry. CONCLUSION: Pulse oximetric measurement of methemoglobin is an early-warning tool for the detection of clinically significant methaemoglobinemia in patients with tumescent local anaesthesia.

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