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Microtubule rescue at midzone edges promotes overlap stability and prevents spindle collapse during anaphase B

During anaphase B, molecular motors slide interpolar microtubules to elongate the mitotic spindle, contributing to the separation of chromosomes. However, sliding of antiparallel microtubules reduces their overlap, which may lead to spindle breakage, unless microtubules grow to compensate sliding. H...

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Detalles Bibliográficos
Autores principales: Lera-Ramirez, Manuel, Nédélec, François J, Tran, Phong T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018073/
https://www.ncbi.nlm.nih.gov/pubmed/35293864
http://dx.doi.org/10.7554/eLife.72630

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