Microfluidic system for near-patient extraction and detection of miR-122 microRNA biomarker for drug-induced liver injury diagnostics

Drug-induced liver injury (DILI) results in over 100 000 hospital attendances per year in the UK alone and is a leading cause for the post-marketing withdrawal of new drugs, leading to significant financial losses. MicroRNA-122 (miR-122) has been proposed as a sensitive DILI marker although no comme...

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Detalles Bibliográficos
Autores principales: Kersaudy-Kerhoas, Maïwenn, Liga, Antonio, Roychoudhury, Appan, Stamouli, Marilena, Grant, Rhiannon, Carrera, Damaso Sanchez, Schulze, Holger, Mielczarek, Witold, Oosthuyzen, Wilna, Quintana, Juan F., Dickinson, Paul, Buck, Amy H., Leslie, Nicholas R., Haas, Jurgen, Bachmann, Till T., Dear, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2022
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018095/
https://www.ncbi.nlm.nih.gov/pubmed/35464137
http://dx.doi.org/10.1063/5.0085078

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