Cargando…

Trehalose Protects Keratinocytes against Ultraviolet B Radiation by Activating Autophagy via Regulating TIMP3 and ATG9A

Trehalose, a natural disaccharide, is synthesized by many organisms when cells are exposed to stressful stimuli. On the basis of its ability to modulate autophagy, trehalose has been considered an innovative drug for ameliorating many diseases, but its molecular mechanism is not well described. Prev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Li, Chen, Hongying, Chen, Xu, Chen, Sihan, Gu, Heng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018197/ https://www.ncbi.nlm.nih.gov/pubmed/35450405 http://dx.doi.org/10.1155/2022/9366494

Ejemplares similares

Trehalose, sucrose and raffinose are novel activators of autophagy in human keratinocytes through an mTOR-independent pathway
por: Chen, Xu, et al.
Publicado: (2016)

Impact on Autophagy and Ultraviolet B Induced Responses of Treatment with the MTOR Inhibitors Rapamycin, Everolimus, Torin 1, and pp242 in Human Keratinocytes
por: Xu, Song, et al.
Publicado: (2017)

Atg11 tethers Atg9 vesicles to initiate selective autophagy
por: Matscheko, Nena, et al.
Publicado: (2019)

Closing the loop: Three musketeers of autophagy-ATG2, ATG18a, and ATG9
por: Mishra, Divya
Publicado: (2023)

The signaling involved in autophagy machinery in keratinocytes and therapeutic approaches for skin diseases
por: Li, Li, et al.
Publicado: (2016)

The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy
por: Rao, Yijian, et al.
Publicado: (2016)

The phenotypes of ATG9, ATG16 and ATG9/16 knock-out mutants imply autophagy-dependent and -independent functions
por: Xiong, Qiuhong, et al.
Publicado: (2015)

Autophagy regulation through Atg9 traffic
por: Reggiori, Fulvio, et al.
Publicado: (2012)

Induction of Autophagy by Baicalin Through the AMPK-mTOR Pathway Protects Human Skin Fibroblasts from Ultraviolet B Radiation-Induced Apoptosis
por: Zhang, Jia-An, et al.
Publicado: (2020)

Phosphorylation of Atg31 is required for autophagy
por: Feng, Wenzhi, et al.
Publicado: (2015)

Autophagy: Multiple Mechanisms to Protect Skin from Ultraviolet Radiation-Driven Photoaging
por: Wang, Mei, et al.
Publicado: (2019)

Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase
por: Papinski, Daniel, et al.
Publicado: (2014)

Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase
por: Papinski, Daniel, et al.
Publicado: (2014)

Quantitative analysis of autophagy reveals the role of ATG9 and ATG2 in autophagosome formation
por: Broadbent, David G., et al.
Publicado: (2023)

Protective Effect of Cyanidin-3-O-Glucoside against Ultraviolet B Radiation-Induced Cell Damage in Human HaCaT Keratinocytes
por: Hu, Yunfeng, et al.
Publicado: (2016)

Isorhamnetin Protects Human Keratinocytes against Ultraviolet B-Induced Cell Damage
por: Han, Xia, et al.
Publicado: (2015)

Silencing the Autophagy-Related Genes ATG3 and ATG9 Promotes SRBSDV Propagation and Transmission in Sogatella furcifera
por: Liu, Dandan, et al.
Publicado: (2022)

Recruitment of Atg9 to the preautophagosomal structure by Atg11 is essential for selective autophagy in budding yeast
por: He, Congcong, et al.
Publicado: (2006)

(125)I Radioactive Particles Drive Protective Autophagy in Hepatocellular Carcinoma by Upregulating ATG9B
por: Xiao, Yunhua, et al.
Publicado: (2023)

Unveiling the Noncanonical Autophagy-Independent Role of ATG7 and ATG9B in Head and Neck Squamous Cell Carcinoma (HNSCC)
por: Guo, Yibo, et al.
Publicado: (2022)

Purpurogallin Protects Keratinocytes from Damage and Apoptosis Induced by Ultraviolet B Radiation and Particulate Matter 2.5
por: Zhen, Ao Xuan, et al.
Publicado: (2019)

ATG9 raises the BAR for PI4P in autophagy
por: Shatz, Oren, et al.
Publicado: (2019)

Salidroside Ameliorates Ultraviolet-Induced Keratinocyte Injury by Inducing SIRT1-Dependent Autophagy
por: Ke, Jin, et al.
Publicado: (2022)

Dual roles of Atg8−PE deconjugation by Atg4 in autophagy
por: Yu, Zhong-Qiu, et al.
Publicado: (2012)

Solar Simulated Ultraviolet Radiation Induces Global Histone Hypoacetylation in Human Keratinocytes
por: Zhang, Xiaoru, et al.
Publicado: (2016)

Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways
por: Mizunoe, Yuhei, et al.
Publicado: (2017)

Molecular Characterization and Functional Analysis of Three Autophagy Genes, BxATG5, BxATG9, and BxATG16, in Bursaphelenchus xylophilus
por: Liu, Hong-Bin, et al.
Publicado: (2019)

TMEM74 promotes tumor cell survival by inducing autophagy via interactions with ATG16L1 and ATG9A
por: Sun, Yizhe, et al.
Publicado: (2017)

Silymarin Protects Epidermal Keratinocytes from Ultraviolet Radiation-Induced Apoptosis and DNA Damage by Nucleotide Excision Repair Mechanism
por: Katiyar, Santosh K., et al.
Publicado: (2011)

Photoprotective Effects of Cannabidiol against Ultraviolet-B-Induced DNA Damage and Autophagy in Human Keratinocyte Cells and Mouse Skin Tissue
por: Li, Yanmei, et al.
Publicado: (2022)

Gasdermin D-mediated keratinocyte pyroptosis as a key step in psoriasis pathogenesis
por: Lian, Ni, et al.
Publicado: (2023)

Autophagy gene Atg7 regulates the development of radiation‐induced skin injury and fibrosis of skin
por: Chen, Xinyi, et al.
Publicado: (2023)

The autophagy protein ATG9A promotes HIV-1 infectivity
por: Mailler, Elodie, et al.
Publicado: (2019)

Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A
por: Abdul Rahim, Siti Aminah, et al.
Publicado: (2017)

Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9
por: Yang, Sisi, et al.
Publicado: (2022)

Oxidation of Atg3 and Atg7 mediates inhibition of autophagy
por: Frudd, Karen, et al.
Publicado: (2018)

NFAT regulates induction of COX-2 and apoptosis of keratinocytes in response to ultraviolet radiation exposure
por: Flockhart, R. J., et al.
Publicado: (2008)

Ultraviolet Radiation Increases the Toxicity of Pyrene, 1-Aminopyrene and 1-Hydroxypyrene to Human Keratinocytes
por: Ekunwe, Stephen I. N., et al.
Publicado: (2005)

Ultraviolet Radiation-Induced Mitochondrial Disturbances Are Attenuated by Metabolites of Melatonin in Human Epidermal Keratinocytes
por: Holtkamp, Chantal E., et al.
Publicado: (2023)

α-Tocopherol protects keratinocytes against ultraviolet A irradiation by suppressing glutathione depletion, lipid peroxidation and reactive oxygen species generation
por: WU, CHI-MING, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_bpj6pr4dm16us2uhfkdqafg2n8