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Genome-Wide Characterization of a Highly Penetrant Form of Hyperlipoprotein(a)emia Associated With Genetically Elevated Cardiovascular Risk
Lp(a) (lipoprotein [a]) is a highly atherogenic lipoprotein strongly associated with coronary artery disease (CAD). Lp(a) concentrations are chiefly determined genetically. Investigation of large pedigrees with extreme Lp(a) using modern whole-genome approaches may unravel the genetic determinants u...
Autores principales: | Coassin, Stefan, Chemello, Kevin, Khantalin, Ilya, Forer, Lukas, Döttelmayer, Patricia, Schönherr, Sebastian, Grüneis, Rebecca, Chong-Hong-Fong, Clément, Nativel, Brice, Ramin-Mangata, Stéphane, Gallo, Antonio, Roche, Mathias, Muelegger, Beatrix, Gieger, Christian, Peters, Annette, Zschocke, Johannes, Marimoutou, Catherine, Meilhac, Olivier, Lamina, Claudia, Kronenberg, Florian, Blanchard, Valentin, Lambert, Gilles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018215/ https://www.ncbi.nlm.nih.gov/pubmed/35133173 http://dx.doi.org/10.1161/CIRCGEN.121.003489 |
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