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Characterization of interactions within the Igα/Igβ transmembrane domains of the human B-cell receptor provides insights into receptor assembly

The B-cell receptor (BCR), a complex comprised of a membrane-associated immunoglobulin and the Igα/β heterodimer, is one of the most important immune receptors in humans and controls B-cell development, activity, selection, and death. BCR signaling plays key roles in autoimmune diseases and lymphopr...

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Detalles Bibliográficos
Autores principales:	Lockey, Christine, Young, Hannah, Brown, Jessica, Dixon, Ann M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018394/ https://www.ncbi.nlm.nih.gov/pubmed/35307351 http://dx.doi.org/10.1016/j.jbc.2022.101843

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