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Disruption of mitochondrial quality control genes promotes caspase-resistant cell survival following apoptotic stimuli

In cells undergoing cell-intrinsic apoptosis, mitochondrial outer membrane permeabilization (MOMP) typically marks an irreversible step in the cell death process. However, in some cases, a subpopulation of treated cells can exhibit a sublethal response, termed “minority MOMP.” In this phenomenon, th...

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Detalles Bibliográficos
Autores principales: Kushnareva, Yulia, Moraes, Vivian, Suess, Julian, Peters, Bjoern, Newmeyer, Donald D., Kuwana, Tomomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018395/
https://www.ncbi.nlm.nih.gov/pubmed/35304098
http://dx.doi.org/10.1016/j.jbc.2022.101835