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LPS-TLR4/MD-2–TNF-α signaling mediates alcohol-induced liver fibrosis in rats
Liver fibrosis results from liver inflammation and progresses to liver cirrhosis or liver cancer. It is known that nonalcoholic liver disease is mediated by the Toll-like receptor 4 (TLR4)/myeloid differentiation factor-2 (MD-2)–tumor necrosis factor-alpha (TNF-α) signaling pathway. This study aimed...
Autores principales: | Mou, Wen-Ling, Chen, Shi-Ru, Wu, Zhen-Ting, Hu, Li-Hua, Zhang, Ji-Ye, Chang, Hong-Jie, Zhou, Hang, Liu, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Toxicologic Pathology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018403/ https://www.ncbi.nlm.nih.gov/pubmed/35516842 http://dx.doi.org/10.1293/tox.2021-0018 |
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