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LPS-TLR4/MD-2–TNF-α signaling mediates alcohol-induced liver fibrosis in rats

Liver fibrosis results from liver inflammation and progresses to liver cirrhosis or liver cancer. It is known that nonalcoholic liver disease is mediated by the Toll-like receptor 4 (TLR4)/myeloid differentiation factor-2 (MD-2)–tumor necrosis factor-alpha (TNF-α) signaling pathway. This study aimed...

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Detalles Bibliográficos
Autores principales: Mou, Wen-Ling, Chen, Shi-Ru, Wu, Zhen-Ting, Hu, Li-Hua, Zhang, Ji-Ye, Chang, Hong-Jie, Zhou, Hang, Liu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018403/
https://www.ncbi.nlm.nih.gov/pubmed/35516842
http://dx.doi.org/10.1293/tox.2021-0018

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