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AAV-PHP.eB transduces both the inner and outer retina with high efficacy in mice

Recombinant adeno-associated virus (AAV) vectors are one of the main gene delivery vehicles used in retinal gene therapy approaches; however, there is a need to further improve the efficacy, tropism, and safety of these vectors. In this study, using a CMV-EGFP expression cassette, we characterize th...

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Detalles Bibliográficos
Autores principales:	Palfi, Arpad, Chadderton, Naomi, Millington-Ward, Sophia, Post, Iris, Humphries, Pete, Kenna, Paul F., Farrar, G. Jane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018541/ https://www.ncbi.nlm.nih.gov/pubmed/35474956 http://dx.doi.org/10.1016/j.omtm.2022.03.016

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