Alcohol-driven metabolic reprogramming promotes development of RORγt-deficient thymic lymphoma

RORγt is a master regulator of Th17 cells. Despite evidence linking RORγt deficiency/inhibition with metastatic thymic T cell lymphomas, the role of RORγt in lymphoma metabolism is unknown. Chronic alcohol consumption plays a causal role in many human cancers. The risk of T cell lymphoma remains unc...

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Detalles Bibliográficos
Autores principales: Sun, Rui, Lei, Chao, Chen, Liang, He, Liqing, Guo, Haixun, Zhang, Xiang, Feng, Wenke, Yan, Jun, McClain, Craig J., Deng, Zhongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018612/
https://www.ncbi.nlm.nih.gov/pubmed/35246617
http://dx.doi.org/10.1038/s41388-022-02257-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018612/
https://www.ncbi.nlm.nih.gov/pubmed/35246617
http://dx.doi.org/10.1038/s41388-022-02257-2

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