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Epigenetic remodelling of Fxyd1 promoters in developing heart and brain tissues

FXYD1 is a key protein controlling ion channel transport. FXYD1 exerts its function by regulating Na(+)/K(+)-ATPase activity, mainly in brain and cardiac tissues. Alterations of the expression level of the FXYD1 protein cause diastolic dysfunction and arrhythmias in heart and decreased neuronal dend...

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Detalles Bibliográficos
Autores principales: Cuomo, Mariella, Florio, Ermanno, Della Monica, Rosa, Costabile, Davide, Buonaiuto, Michela, Di Risi, Teodolinda, De Riso, Giulia, Sarnataro, Antonella, Cocozza, Sergio, Visconti, Roberta, Chiariotti, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018693/
https://www.ncbi.nlm.nih.gov/pubmed/35440736
http://dx.doi.org/10.1038/s41598-022-10365-y