Targeting colonic macrophages improves glycemic control in high-fat diet-induced obesity

The obesity epidemic continues to worsen worldwide. However, the mechanisms initiating glucose dysregulation in obesity remain poorly understood. We assessed the role that colonic macrophage subpopulations play in glucose homeostasis in mice fed a high-fat diet (HFD). Concurrent with glucose intoler...

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Detalles Bibliográficos
Autores principales: Rohm, Theresa V., Keller, Lena, Bosch, Angela J. T., AlAsfoor, Shefaa, Baumann, Zora, Thomas, Amandine, Wiedemann, Sophia J., Steiger, Laura, Dalmas, Elise, Wehner, Josua, Rachid, Leila, Mooser, Catherine, Yilmaz, Bahtiyar, Fernandez Trigo, Nerea, Jauch, Annaise J., Wueest, Stephan, Konrad, Daniel, Henri, Sandrine, Niess, Jan H., Hruz, Petr, Ganal-Vonarburg, Stephanie C., Roux, Julien, Meier, Daniel T., Cavelti-Weder, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018739/
https://www.ncbi.nlm.nih.gov/pubmed/35440795
http://dx.doi.org/10.1038/s42003-022-03305-z

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