Loss of vascular endothelial notch signaling promotes spontaneous formation of tertiary lymphoid structures

Tertiary lymphoid structures (TLS) are lymph node-like immune cell clusters that emerge during chronic inflammation in non-lymphoid organs like the kidney, but their origin remains not well understood. Here we show, using conditional deletion strategies of the canonical Notch signaling mediator Rbpj...

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Detalles Bibliográficos
Autores principales: Fleig, Susanne, Kapanadze, Tamar, Bernier-Latmani, Jeremiah, Lill, Julia K., Wyss, Tania, Gamrekelashvili, Jaba, Kijas, Dustin, Liu, Bin, Hüsing, Anne M., Bovay, Esther, Jirmo, Adan Chari, Halle, Stephan, Ricke-Hoch, Melanie, Adams, Ralf H., Engel, Daniel R., von Vietinghoff, Sibylle, Förster, Reinhold, Hilfiker-Kleiner, Denise, Haller, Hermann, Petrova, Tatiana V., Limbourg, Florian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018798/
https://www.ncbi.nlm.nih.gov/pubmed/35440634
http://dx.doi.org/10.1038/s41467-022-29701-x

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