Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes

Astroblastomas (ABs) are rare brain tumors of unknown origin. We performed an integrative genetic and epigenetic analysis of AB-like tumors. Here, we show that tumors traceable to neural stem/progenitor cells (radial glia) that emerge during early to later brain development occur in children and you...

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Detalles Bibliográficos
Autores principales: Lehman, Norman L., Spassky, Nathalie, Sak, Müge, Webb, Amy, Zumbar, Cory T., Usubalieva, Aisulu, Alkhateeb, Khaled J., McElroy, Joseph P., Maclean, Kirsteen H., Fadda, Paolo, Liu, Tom, Gangalapudi, Vineela, Carver, Jamie, Abdullaev, Zied, Timmers, Cynthia, Parker, John R., Pierson, Christopher R., Mobley, Bret C., Gokden, Murat, Hattab, Eyas M., Parrett, Timothy, Cooke, Ralph X., Lehman, Trang D., Costinean, Stefan, Parwani, Anil, Williams, Brian J., Jensen, Randy L., Aldape, Kenneth, Mistry, Akshitkumar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018799/
https://www.ncbi.nlm.nih.gov/pubmed/35440587
http://dx.doi.org/10.1038/s41467-022-29302-8

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